Preferred Label : 4-Methoxyestrone;
NCIt synonyms : 4-OMeE1; 4-MeE1; 4-MeOE1;
NCIt definition : A metabolite formed during the methylation of 4-hydroxyestrone (4-OHE1) by catechol-O-methyltransferase
(COMT) and devoid of any oncogenic or anticarcinogenic activities. The 4-methoxyestrone
(4-MeOE1):4-OHE1 ratio can be used to assess methylation efficiency and cancer risk.
Lower 4-MeOE1:4-OHE1 ratios suggest inadequate methylation and increased risk of certain
cancers.;
Origin ID : C120470;
UMLS CUI : C4053546;
Semantic type(s)
- concept_is_in_subset
