Preferred Label : Large-Scale State Transition;
NCIt synonyms : LST; Large Scale State Transition;
NCIt definition : Chromosomal breakage that generates 10 Mb or larger fragments. The quantification
of these breaks can be used as a surrogate measure for genomic instability, which
may be caused by mutation of DNA repair genes, including BRCA1 or BRCA2.;
PubMed : 22933060;
Origin ID : C120466;
UMLS CUI : C4054667;
Semantic type(s)
- concept_is_in_subset
