Preferred Label : Polysaccharide-K;
NCIt synonyms : KS-2; PSK;
NCIt related terms : Glycoproteins;
NCIt definition : A protein-bound polysaccharide derived from the mushroom Trametes versicolor (Turkey
Tail) with immunoadjuvant and potential antitumor activities. Although its mechanism
of action has yet to be fully elucidated, in vitro and in vivo studies indicate that
polysaccharide-K induces peripheral blood monocyte secretion of IL-8 and TNF-alpha,
induces T cell proliferation, and prevents cyclophosphamide-induced immunosuppression.
This agent has also been reported to stimulate macrophages to produce reactive nitrogen
intermediates and superoxide anions and to promote apoptosis in the promyelocytic
leukemia cell line HL-60.;
CAS number : 66455-27-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 66455-27-4
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G-SRS /a ;
Drug name : Krestin;
Codes from synonyms : 01719;
Origin ID : C1204;
UMLS CUI : C0072522;
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset