Preferred Label : Recombinant Prothymosin Alpha;
NCIt synonyms : Prothymosin Alpha; Therapeutic Prothymosin Alpha;
NCIt definition : A recombinant form of the endogenous polypeptide hormone that exerts immunomodulatory
effects primarily on mononuclear cells. Prothymosin alpha stimulates the production
of various cytokines including granulocyte/macrophage colony stimulating factor (GM-CSF)
alpha, gamma interferon (IFN) and interleukins such as IL-2. This agent may also increase
some tumor antigens expression, thus inducing better T lymphocyte responses to tumor
cells. Combined with chemotherapy, prothymosin alpha may exhibit significant anti-tumor
effects. This agent also helps to regenerate lymph node and bone marrow cells after
treatment with certain toxic chemotherapeutics. (NCI04);
Origin ID : C1203;
UMLS CUI : C1527078;
Currated CISMeF NLP mapping
- Semantic type(s)
