CIC-DUX4 Fusion Protein Expression

Preferred Label : CIC-DUX4 Fusion Protein Expression;

NCIt definition : Expression of a fusion protein that results from a t(4;19)(q35;q13) translocation, which involves the human genes CIC (capicua transcriptional suppressor) and DUX4 (double homeobox 4).;

NCIt note : There is some conflicting information in the literature and various molecular genetic databases regarding whether the CIC gene fusion partner is the DUX4 gene or its nearby pseudogene, DUX4L1.;

Détails

Origin ID

C120220;

UMLS CUI

C3899763;

Molecular abnormality of diseases
- Metastatic Undifferentiated Round Cell Sarcoma [NCIt concept]
- Undifferentiated Round Cell Sarcoma [NCIt concept]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
is_molecular_abnormality_of_disease
- CIC-DUX4 Sarcoma [NCIt concept]
molecular_abnormality_involves_gene
- CIC Gene [NCIt concept]
- CIC/DUX4 Fusion Gene [NCIt concept]
- DUX4 Gene [NCIt concept]
related_to_genetic_biomarker
- CIC Gene [NCIt concept]
- DUX4 Gene [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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