Roblitinib - CISMeF

Preferred Label : Roblitinib;

NCIt synonyms : FGFR4 Inhibitor FGF401;

NCIt definition : An inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, roblitinib binds to and inhibits the activity of FGFR4, which leads to an inhibition of tumor cell proliferation in FGFR4-overexpressing cells. FGFR4 is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cell proliferation, differentiation, angiogenesis, and survival.;

UNII : M64JF6WMSA;

InChIKey : BHKDKKZMPODMIQ-UHFFFAOYSA-N;

CAS number : 1708971-55-4;

Molecule name : FGF401;

NCI Metathesaurus CUI : CL507817;

Details

Origin ID

C120102;

UMLS CUI

C5421267;

Currated CISMeF NLP mapping
- roblitinib [MeSH concept]
- roblitinib [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- roblitinib [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Fibroblast Growth Factor Receptor 4 [NCIt concept]

Keyword's position in hierarchy(ies) :

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