" /> Cibisatamab - CISMeF





Preferred Label : Cibisatamab;

NCIt definition : An anti-carcinoembryonic antigen (CEA)/anti-CD3 bispecific monoclonal antibody with potential antineoplastic activity. Cibisatamab contains two antigen-recognition sites: one for human CD3, a T-cell surface antigen, and one for human CEA, a tumor-associated antigen that is specifically expressed on certain tumor cells. Upon intravenous administration, cibisatamab binds to both T-cells and CEA-expressing tumor cells, which cross-links the T-cells with the tumor cells. This may result in a potent cytotoxic T-lymphocyte (CTL) response against CEA-expressing tumor cells. CEA is overexpressed in many cancer cell types.;

UNII : ZAM5J1ATF2;

CAS number : 1855925-27-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1855925-27-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : RO6958688; RG-7802; WHO 10636;

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09/05/2024


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