Preferred Label : Fluorine F 18-labeled 2-FACPC;
NCIt synonyms : 1-Amino-2-[18F]fluorocyclopentane-1-carboxylic Acid; Anti-2-[(18)F]FACPC; 2-[18F]FACPC; Anti-1-amino-2-[18F]fluorocyclopentyl-1-carboxylic Acid; 2-[(18)F]FACPC;
NCIt definition : A radioconjugate composed of an analog of the synthetic, alicyclic amino acid aminocyclopentane
carboxylic acid (ACPC) radiolabeled with the positron-emitting isotope fluorine F
18 (2-[18F]FACPC), with potential cancer cell imaging activity during positron emission
tomography (PET). As tumor cells have a higher rate of protein synthesis than normal,
healthy cells, upon administration, fluorine F 18 labeled 2-FACPC is selectively taken
up by rapidly proliferating tumor cells through the sodium-independent subtype L amino
acid transport system (AAT) which leads to the accumulation of this tracer in tumor
cells. Upon PET, tumor cells can then be visualized.;
Origin ID : C120070;
UMLS CUI : C3896948;
Semantic type(s)
- concept_is_in_subset
