" /> Poly ICLC - CISMeF





Preferred Label : Poly ICLC;

NCIt synonyms : Polyinosinic-Polycytidylic Acid Stabilized with Polylysine and Carboxymethylcellulose; Stabilized Polyriboinosinic/Polyribocytidylic Acid; PolyI:PolyC with Poly-L-Lysine Stabilizer; Poly I:Poly C with Poly-L-Lysine Stabilizer; Polyriboinosinic-Polyribocytidylic Acid-Polylysine Carboxymethylcellulose;

NCIt related terms : HILTONOL; poly-ICLC;

NCIt definition : A synthetic complex of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA. Poly ICLC may stimulate the release of cytotoxic cytokines and, by inducing interferon-gamma production, may increase the tumoricidal activities of various immunohematopoietic cells. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer and for its ability to stimulate the immune system. It is made in the laboratory by combining the nucleic acid RNA with the chemicals poly-L-lysine and carboxymethyl cellulose.;

UNII : 7KYP9TKT70;

CAS number : 59789-29-6;

Drug name : Hiltonol;

NSC code : 301463;

Codes from synonyms : NSC0301463; CDR0000305996;

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Keyword's position in hierarchy(ies) : arborescence

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06/07/2025


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