Preferred Label : Allogeneic Cellular Vaccine 1650-G;
NCIt synonyms : 1650-G Vaccine;
NCIt definition : A pluripotent, allogeneic, tumor cell vaccine composed of irradiated tumor cells from
the non-small cell lung cancer (NSCLC) cell line 1650 and the immunoadjuvant recombinant
granulocyte-macrophage colony stimulating factor (GM-CSF) (1650-G), with potential
immunostimulating and antineoplastic activities. Upon administration, allogeneic cellular
vaccine 1650-G may stimulate the immune system to exert a cytotoxic T-lymphocyte (CTL)
immune response against tumor-associated antigens (TAAs) expressed on NSCLC cells.
GM-CSF potentiates the antitumor immune response. The 1650 cell line is used as a
source for TAAs.;
Molecule name : 1650-G;
Origin ID : C119759;
UMLS CUI : C3896934;
Semantic type(s)
- concept_is_in_subset
