Tribbles Homolog 1

Preferred Label : Tribbles Homolog 1;

NCIt synonyms : SKIP1; G-Protein-Coupled Receptor-Induced Protein 2; G-Protein-Coupled Receptor-Induced Gene 2 Protein; Phosphoprotein Regulated By Mitogenic Pathways; TRB-1; Tribbles-Like Protein 1; GIG-2;

NCIt definition : Tribbles homolog 1 (372 aa, 41 kDa) is encoded by the human TRIB1 gene. This protein plays a role in the regulation of MAP kinase activity.;

NCIt note : Tribbles homolog 1 is homologous to protein serine-threonine kinases, but is lacking the active site lysine and has no catalytic activity. (OMIM);

Details

Origin ID

C119630;

UMLS CUI

C1528889;

Automatic exact mappings (from CISMeF team)
- Taste receptor, type 2, member 14 [OMIM gene]
- Tribbles pseudokinase 1 [OMIM gene]
OMIM relation
- Tribbles pseudokinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TRIB1 protein, human [MeSH Supplementary Concept]
- TRIB1 protein, human [MeSH concept]
gene_encodes_gene_product
- Signaling Pathway Gene [NCIt concept]
- TRIB1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_plays_role_in_biological_process
- Enzyme Activity Alteration [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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