Preferred Label : ARC Definite Stent Thrombosis;
NCIt related terms : STENT THROMBOSIS ARC GRADE DEFINITE;
Alternative definition : CDISC: Includes acute ischemic symptoms at rest, acute post ischemic ECG, positive
biomarkers and pathological evidence. Definite stent thrombosis is considered to have
occurred when there is either angiographic or pathological confirmation. Angiographic
confirmation is the presence of a thrombus at coronary angiography that originates
in the stent or in the segment 5 mm proximal or distal to the stent, with the presence
of at least 1 of 3 clinical criteria within a 48-hour time window: 1) acute onset
of ischemic symptoms at rest; 2) new ischemic ECG changes that suggest acute ischemia;
or 3) typical rise and fall in cardiac biomarkers. Pathological confirmation is evidence
of recent thrombus within the stent determined at autopsy or via examination of tissue
retrieved following thrombectomy. (Cutlip DE, Windecker S, Mehran R, et al. Clinical
End Points in Coronary Stent Trials : A Case for Standardized Definitions. Circulation.
2007;115:2344-2351);
Origin ID : C119598;
UMLS CUI : C3900164;
Semantic type(s)
concept_is_in_subset