NCIt definition : The resistance to blood flow offered by the pulmonary vasculature, which is normally
one sixth of SVR. The major determinant of PVR is pulmonary vessel constriction, most
often caused by hypoxia and/or hypercarbia. Prolonged elevated PVR can cause right
heart failure.;
Alternative definition : CDISC: The resistance to blood flow through the pulmonary vasculature.; ACC/AHA: Pulmonary vascular resistance is calculated as (mean PA pressure minus mean
pulmonary capillary wedge pressure) divided by cardiac output.;