Preferred Label : Increase in B-type Natriuretic Peptide or N-terminal pro-B-type Natriuretic Peptide;
NCIt related terms : INCREASE IN HEART FAILURE BIOMARKER;
NCIt definition : A finding of an increased amount of either B-type natriuretic peptide or N-terminal
pro-B-type natriuretic peptide;
Alternative definition : CDISC: Biomarker increase (B-type natriuretic peptide (BNP)/ N-terminal pro-BNP (NT-proBNP))
consistent with decompensation of heart failure (such as BNP greater than 500 pg/mL
or NT-proBNP greater than 2,000 pg/mL). In patients with chronically elevated natriuretic
peptides, a significant increase above baseline is required. (Hicks KA, Tcheng JE,
Bozkurt B, Chaitman BR, Cutlip DE, Farb A, Fonarow GC, Jacobs JP, Jaff MR, Lichtman
JH, Limacher MC, Mahaffey KW, Mehran, R, Nissen SE, Smith EE, Targum SL. 2014 ACC/AHA
Key Data Elements and Definitions For Cardiovascular Endpoint Events In Clinical Trials:
a report of the American College of Cardiology/American Heart Association Task Force
on Clinical Data Standards (Writing Committee to Develop Cardiovascular End Points
Data Standards) J Am Coll Cardiol 2014; In Press);
Origin ID : C119205;
UMLS CUI : C3898772;
Semantic type(s)
- concept_is_in_subset
- related_to_genetic_biomarker
