NCIt definition : Human LZTS1 wild-type allele is located in the vicinity of 8p22 and is approximately
58 kb in length. This allele, which encodes leucine zipper putative tumor suppressor
1 protein, is involved in cell cycle regulation, cell growth modulation, transcriptional
regulation, and tumor suppression. Mutation of the gene is associated with esophageal
squamous cell carcinoma and several other neoplastic diseases.;