" /> Penclomedine - CISMeF





Preferred Label : Penclomedine;

NCIt synonyms : 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl) pyridine; PEN;

NCIt related terms : Pyridine, 3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)-;

NCIt definition : A synthetic derivative of pyrimidine with antineoplastic activity. Penclomedine alkylates and crosslinks DNA, resulting in DNA strand breaks and inhibition of DNA and RNA synthesis. This agent is more active against tumor cells that are defective in p53 function. (NCI04);

Alternative definition : NCI-GLOSS: A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called alkylating agents.;

UNII : 66Q80IL7CW;

InChIKey : DZVPGIORVGSQMC-UHFFFAOYSA-N;

CAS number : 108030-77-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 108030-77-9 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : CRC 88-04;

Chemical formula : C8H6Cl5NO2;

NSC code : 338720;

Codes from synonyms : NSC0338720; CDR0000045411;

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13/05/2024


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