Preferred Label : VEGFR/FGFR Inhibitor ODM-203;
NCIt related terms : ODM-203;
NCIt definition : An orally available inhibitor of the human vascular endothelial growth factor receptors
(VEGFRs) and fibroblast growth factor receptors (FGFRs), with potential antiangiogenic
and antineoplastic activities. VEGFR/FGFR inhibitor ODM-203 inhibits both VEGFRs and
FGFRs, which may result in the inhibition of VEGFR- and FGFR-mediated signaling. This
leads to an inhibition of angiogenesis and cell proliferation in tumor cells overexpressing
VEGFR and/or FGFR. Both VEGFRs and FGFRs belong to the superfamily of receptor tyrosine
kinases and are upregulated in various tumor cell types.;
UNII : Y7HJ4D4CRT;
CAS number : 1430723-35-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1430723-35-5
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G-SRS /a ;
Molecule name : ODM 203; ODM-203;
Origin ID : C118628;
UMLS CUI : C3896799;
Semantic type(s)
- concept_is_in_subset
