Preferred Label : Ubidecarenone Nanodispersion BPM31510n;
NCIt synonyms : Coenzyme Q10 Injectable Nanosuspension; Ubiquinone Injectable Nanosuspension;
NCIt related terms : Ubidecarenone Injectable Nanosuspension;
NCIt definition : A nanodispersion containing the benzoquinone ubidecarenone (coenzyme Q10), with potential
protective, antioxidant and antineoplastic activities. Upon administration, ubidecarenone
nanodispersion BPM31510 modulates tumor cell metabolism and causes an anti-Warburg
effect by inducing a shift from lactate dependency towards mitochondrial oxidative
phosphorylation, and induces tumor cell apoptosis. This inhibits tumor cell proliferation.
BPM 31510 also induces the activation and maturation of T-lymphocytes, and changes
the surface expression of certain immune checkpoint modulators. In addition, as an
antioxidant, ubidecarenone protects against cell damage, by preventing both the peroxidation
of lipid membranes and the oxidation of LDL-cholesterol. Ubidecarenone is an essential
coenzyme for mitochondrial enzyme complexes involved in oxidative phosphorylation
and the production of adenosine triphosphate (ATP).;
Molecule name : BP31510;
Origin ID : C118621;
UMLS CUI : C3897258;
Semantic type(s)
- concept_is_in_subset
