Preferred Label : Gamboge Resin Extract TSB-9-W1;
NCIt synonyms : Garcinia Hanburyi Rhizome Resin;
NCIt related terms : GARCINIA HANBURYI ROOT RESIN;
NCIt definition : An orally bioavailable extract from the yellow to brown gum-resin of the gamboge tree
(genus Garcinia) belonging to the Clusiaceae (or Guttiferae) family, with potential
anti-inflammatory and antineoplastic activities. Gamboge resin extract TSB-9-W1 contains
various active ingredients, including gambogic acid, formoxanthone A, betulin, betulinic
acid, morellic acid, isomorellic acid, isogambogic acid, isomorellinol and desoxymorellin.
Upon oral administration, the various active components of the gamboge resin extract
TSB-9-W1 may bind to and inhibit the activity of a variety of cancer-related proteins,
may induce apoptosis, and may exert cytotoxic activity on tumor cells, thereby inhibiting
tumor cell proliferation. TSB-9 is derived from TSB-14, which is the acetone-extract
of gamboge resin, and pulverized into powder form; TSB-9 is 90% extract and 10% brown
sugar. TSB-9-W1 is a milled form of TSB-9 with a particle size of 5 micrometers.;
UNII : KQR4YN4C28;
Molecule name : TSB-9-W1;
Origin ID : C118444;
UMLS CUI : C3896755;
Semantic type(s)
- concept_is_in_subset
