" /> ABO wt Allele - CISMeF





Preferred Label : ABO wt Allele;

NCIt synonyms : ABO Blood Group (Transferase A, Alpha 1-3-N-Acetylgalactosaminyltransferase; Transferase B, Alpha 1-3-Galactosyltransferase) wt Allele; GTB; A3GALT1; A3GALNT; NAGAT;

NCIt definition : Human ABO wild-type allele is located in the vicinity of 9q34.2 and is approximately 2 kb in length. This allele, which encodes histo-blood group ABO system transferase protein, plays a role in blood group determination. Variation of the gene determines whether the protein can catalyze the transfer of carbohydrates to the H antigen to form carbohydrate antigen A or B on the surface of red blood cells.;

NCIt note : The O phenotype results from a single base frameshift in the ABO gene, which encodes a truncated protein that lacks catalytic activity.;

GenBank Accession Number : AF134415;

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07/05/2025


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