" /> Zorifertinib - CISMeF





Preferred Label : Zorifertinib;

NCIt definition : An orally available inhibitor of the epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Upon oral administration, zorifertinib binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR. This prevents EGFR-mediated signaling, and may lead to both induction of cell death and inhibition of tumor growth in EGFR-overexpressing cells. EGFR, a receptor tyrosine kinase mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization.;

UNII : 67SX9H68W2;

InChIKey : MXDSJQHFFDGFDK-CYBMUJFWSA-N;

CAS number : 1626387-80-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1626387-80-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : AZD3759;

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Keyword's position in hierarchy(ies) : arborescence

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15/05/2024


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