Leukemia-Associated Non-Coding IGF1R Activator RNA 1

Preferred Label : Leukemia-Associated Non-Coding IGF1R Activator RNA 1;

NCIt synonyms : Leukemia-Induced Noncoding Activator RNA; LUNAR1;

NCIt definition : Leukemia-associated non-coding IGF1R activator RNA 1 is encoded by the human LUNAR1 gene. This non-coding RNA plays a role in both leukemogenesis and Notch signaling.;

NCIt note : Leukemia-associated non-coding IGF1R activator RNA 1 appears to enhance expression of the IGF1R gene, which leads to increased cell proliferation. (Cell. 2014; 158: 593-606.);

PubMed : 25083870;

Details

Origin ID

C118120;

UMLS CUI

C3890044;

Automatic exact mappings (from CISMeF team)
- leukemia-associated non-coding IGF1R activator RNA 1 [HGNC gene]
Semantic type(s)
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
gene_encodes_gene_product
- LUNAR1 Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_plays_role_in_biological_process
- Gene Regulation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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