Olsalazine - CISMeF

Preferred Label : Olsalazine;

NCIt synonyms : C.I. Mordant Yellow 5; Azodisalicylate; 3,3'-Azobis[6-hydroxybenzoic Acid]; 3,3'-Dicarboxy-4,4'-dihydroxyazobenzene;

NCIt definition : A prodrug of mesalamine (5-Aminosalicylic acid; 5-ASA) with anti-inflammatory activity. Unabsorbed olsalazine passes through gastrointestinal tract and is cleaved by azoreductases, produced by microflora in colon, into 2 active molecules of 5-ASA. 5-ASA exerts its anti-inflammatory action locally by inhibiting cyclooxygenase and lipoxygenase activities, thereby reducing the production of prostaglandins and leukotrienes. In addition, mesalamine may act as a scavenger of reactive oxygen free radicals.;

UNII : ULS5I8J03O;

InChIKey : QQBDLJCYGRGAKP-FOCLMDBBSA-N;

CAS number : 15722-48-2;

Chemical formula : C14H10N2O6;

ChEBI ID : CHEBI:7770;

Codes from synonyms : 00801;

Details

Origin ID

C1176;

UMLS CUI

C0069454;

Currated CISMeF NLP mapping
- Olsalazine [ICD-11 Extension code]
- Olsalazine [ICHI extension code]
- Olsalazine [SMS substance]
- Olsalazine (substance) [SNOMED CT concept]
- Product containing olsalazine (medicinal product) [SNOMED CT concept]
- olsalazine [MeSH concept]
- olsalazine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Olsalazine [ICD-11 Extension code]
- Olsalazine (substance) [SNOMED CT concept]
- Product containing olsalazine (medicinal product) [SNOMED CT concept]
- olsalazine [ATC Code]
- olsalazine [MeSH concept]
- olsalazine [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- olsalazine [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_salt_form
- Olsalazine Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Olsalazine Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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