" /> Tusamitamab Ravtansine - CISMeF





Preferred Label : Tusamitamab Ravtansine;

NCIt synonyms : ADC SAR408701; Anti-CEACAM5 Antibody-Drug Conjugate SAR408701;

NCIt definition : An immunoconjugate consisting of anti-carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) conjugated to a cytotoxic agent, with potential antineoplastic activity. Upon administration of tusamitamab ravtansine the antibody moiety targets CEACAM5 on tumor cells. Upon antibody/antigen binding and internalization, the immunoconjugate releases the cytotoxic agent, which results in tumor cell death. CEACAM5, a member of the CEA family of proteins that plays a key role in cell migration, cell invasion, and cell adhesion, is overexpressed by a variety of cancer cell types.;

UNII : DSS3BE2ZXN;

CAS number : 2254086-60-5; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2254086-60-5 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : SAR408701;

NCI Metathesaurus CUI : CL474097;

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Keyword's position in hierarchy(ies) : arborescence

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12/05/2024


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