APOBEC3A_B Fusion Hybrid Gene

Preferred Label : APOBEC3A_B Fusion Hybrid Gene;

NCIt synonyms : CTA-150C2.14-001; APOBEC3A and APOBEC3B Deletion Hybrid Gene;

NCIt related terms : APOBEC3A_B;

NCIt definition : A fusion gene ( 10 kb) that results from the deletion of approximately 29.5 kb of sequence between the APOBEC3A gene and the adjacent APOBEC3B gene. The deletion hybrid is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. This mutation results in an APOBEC3B null phenotype, which would impact antiretroviral defense processes, and may be associated with an increased risk of breast carcinoma and other neoplastic diseases.;

GenBank Accession Number : GL383583;

PubMed : 17447845;

Details

Origin ID

C117006;

UMLS CUI

C3540384;

Currated CISMeF NLP mapping
- APOBEC3A and APOBEC3B deletion hybrid [HGNC gene]
HGNC gene
- APOBEC3A and APOBEC3B deletion hybrid [HGNC gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- APOBEC3A and APOBEC3B deletion hybrid [HGNC gene]
related_to_genetic_biomarker
- APOBEC3A Gene [NCIt concept]
- APOBEC3B Gene [NCIt concept]

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