APOBEC3B wt Allele

Preferred Label : APOBEC3B wt Allele;

NCIt synonyms : FLJ21201; A3B; ARP4; bK150C2.2; Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3B wt Allele; APOBEC1L; DJ742C19.2; ARCD3; PHRBNL;

NCIt definition : Human APOBEC3B wild-type allele is located within 22q13.1-q13.2 and is approximately 10 kb in length. This allele, which encodes DNA dC- dU-editing enzyme APOBEC-3B protein, is involved in the modulation of DNA cytosine deamination. A deletion that fuses the 3' UTR of this gene to the 3' end of the APOBEC3A gene, essentially deletes the APOBEC3B coding sequence, and may be associated with increased susceptibility to neoplastic disease.;

NCIt note : The APOBEC3B gene is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. (EntrezGene);

GenBank Accession Number : AK024854;

PubMed : 17447845;

Details

Origin ID

C117002;

UMLS CUI

C3890224;

Automatic exact mappings (from CISMeF team)
- actin like 6A [ORDO Gene]
- sarcoglycan beta [ORDO Gene]
OMIM relation
- Apolipoprotein b mrna-editing enzyme, catalytic polypeptide-like 3b [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 22q13.1-q13.2 [NCIt concept]
gene_plays_role_in_process
- Antiviral Response [NCIt concept]
- Hydrolysis [NCIt concept]
- Immunity [NCIt concept]

Keyword's position in hierarchy(ies) :

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