APOBEC3A wt Allele

Preferred Label : APOBEC3A wt Allele;

NCIt synonyms : A3A; ARP3; bK150C2.1; Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A wt Allele; PHRBN;

NCIt definition : Human APOBEC3A wild-type allele is located within 22q13.1-q13.2 and is approximately 10 kb in length. This allele, which encodes DNA dC- dU-editing enzyme APOBEC-3A protein, plays a role in the modulation of viral DNA modification. A deletion that fuses this gene and the 3' end of the APOBEC3B gene may be associated with increased susceptibility to neoplastic disease.;

NCIt note : The APOBEC3A gene is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. (EntrezGene);

GenBank Accession Number : U03891;

PubMed : 17447845;

Details

Origin ID

C116999;

UMLS CUI

C3890223;

Automatic exact mappings (from CISMeF team)
- Actin-related protein 3 [OMIM gene]
- dystroglycan 1 [ORDO Gene]
OMIM relation
- Apolipoprotein b mrna-editing enzyme, catalytic polypeptide-like 3a [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 22q13.1-q13.2 [NCIt concept]
gene_plays_role_in_process
- Antiviral Response [NCIt concept]
- Hydrolysis [NCIt concept]
- Immunity [NCIt concept]

Keyword's position in hierarchy(ies) :

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