FMO3 wt Allele

Preferred Label : FMO3 wt Allele;

NCIt synonyms : TMAU; Flavin Containing Monooxygenase 3 Gene; dJ127D3.1; FMOII; Flavin Containing Dimethylaniline Monoxygenase 3 wt Allele;

NCIt definition : Human FMO3 wild-type allele is located in the vicinity of 1q24.3 and is approximately 27 kb in length. This allele, which encodes flavin-containing monooxygenase 3 protein, plays a role in the oxygenation of drugs, dietary supplements and pesticides. Mutation of the gene is associated with trimethylaminuria.;

GenBank Accession Number : BC032016;

Details

Origin ID

C116953;

UMLS CUI

C3890188;

Automatic exact mappings (from CISMeF team)
- N,N-dimethylaniline monooxygenase activity [GO term]
- Severe primary trimethylaminuria [ORDO Disease]
- Trimethylaminuria [OMIM Phenotype]
- flavin containing dimethylaniline monoxygenase 3 [ORDO Gene]
OMIM relation
- Flavin-containing dimethylaniline monooxygenase 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1q24.3 [NCIt concept]
gene_is_element_in_pathway
- Drug Metabolism by Cytochrome P450 Pathway [NCIt concept]
- Taurine and Hypotaurine Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Drug Metabolism Induction [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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