Preferred Label : CNS 2;
NCIt related terms : CNS2; Central Nervous System Status 2;
NCIt definition : The status of central nervous system leukemia at diagnosis, where there are less than
5 white blood cells per microliter on a cerebral spinal fluid cytospin preparation
that is positive for blasts; or greater than 5 white blood cells per microliter on
a cerebral spinal fluid cytospin preparation that is considered negative by Steinherz/Bleyer
algorithm.;
Alternative definition : CDISC: Central nervous system status defined as puncture nontraumatic with less than
or equal to 5 WBC/uL in cerebral spinal fluid with identifiable blasts.(Smith M, Arthur
D, Camitta B, Carroll AJ, Crist W, Gaynon P, Gelber R, Heerema N, Korn EL, Link M,
Murphy S, Pui CH, Pullen J, Reamon G, Sallan SE, Sather H, Shuster J, Simon R, Trigg
M, Tubergen D, Uckun F, Ungerleider R. Uniform approach to risk classification and
treatment assignment for children with acute lymphoblastic leukemia. J Clin Oncol.
1996 Jan;14(1):18-24.);
Origin ID : C116834;
UMLS CUI : C3899749;
False automatic mappings
Semantic type(s)
concept_is_in_subset