Pinaverium Bromide

Preferred Label : Pinaverium Bromide;

NCIt synonyms : Morpholinium, 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-yl)ethoxy]ethyl]-, Bromide; 4-(6-Bromoveratryl)-4-(2-(2-(6,6-dimethyl-2-norpinyl)ethoxy)ethyl)morpholinium Bromide;

NCIt definition : An orally available bromide salt form of pinaverium, a calcium channel blocker (CCB) with antispasmodic activity. Upon oral administration, pinaverium blocks the voltage-dependent calcium channels and inhibits calcium ion influx into the smooth muscle cells located in the gastrointestinal (GI) tract. This prevents smooth muscle contraction and relaxes the GI tract. In addition, pinaverium may both reduce bowel uptake of and facilitate the function of locally active, co-administered drugs.;

UNII : 7SCF54H12J;

InChIKey : IKGXLCMLVINENI-QOXGANSBSA-M;

CAS number : 53251-94-8;

Drug name : Pinverin;

Details

Origin ID

C116775;

UMLS CUI

C0137073;

Currated CISMeF NLP mapping
- Pinaverium [ICD-11 Extension code]
- Pinaverium bromide [ICHI extension code]
- Pinaverium bromide [SMS substance]
- Pinaverium bromide (substance) [SNOMED CT concept]
- pinaverium [MeSH Supplementary Concept]
- pinaverium bromide [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pinaverium [ICD-11 Extension code]
- Pinaverium bromide (substance) [SNOMED CT concept]
- pinaverium bromide [MeSH concept]
Validated automatic mappings to NTBT
- Pinaverium [SMS substance]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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