Pro-Interleukin-16

Preferred Label : Pro-Interleukin-16;

NCIt synonyms : Prointerleukin-16; Pro-IL-16; nPro-IL-16; Prointerleukin 16;

NCIt definition : Pro-interleukin-16 (1332 aa, 142 kDa) is encoded by the human IL16 gene. This protein is involved in both transcriptional repression and cytokine signaling.;

NCIt note : Pro-interleukin-16 is expressed as three isoforms that are the result of alternative splicing. All three isoforms may be proteolytically processed by caspase-3 to form interleukin-16. (UniProt);

Details

Origin ID

C116765;

UMLS CUI

C3888288;

Automatic exact mappings (from CISMeF team)
- interleukin 16 [HGNC gene]
- interleukin 16 precursor [MeSH Supplementary Concept]
OMIM relation
- Interleukin 16 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IL16 Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- PDZ Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Chemotactic Process [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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