NCIt synonyms : MDL 63,397; Ristomycin A Aglycone, 5,31-Dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-(2-deoxy-2-((10-methyl-1-oxoundecyl)amino)-beta-D-glucopyranuronosyl)-38-(((3-(dimethylamino)propyl)amino)carbonyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-;
NCIt definition : A second-generation, semi-synthetic lipoglycopeptide antibiotic, with bactericidal
activity against a variety of gram-positive bacteria. Upon administration, dalbavancin
binds, at a site different from that of penicillins and cephalosporins, tightly to
the D-alanyl-D-alanine portion of peptidoglycan chains, thereby preventing peptidoglycan
elongation and interfering with bacterial cell wall synthesis. This leads to activation
of bacterial autolysins and induces cell wall lysis.;