Anti-CD33 Monoclonal Antibody BI 836858

Preferred Label : Anti-CD33 Monoclonal Antibody BI 836858;

NCIt related terms : BI-836858;

NCIt definition : An engineered, fully human, immunoglobulin (Ig) G1 anti-CD33 monoclonal antibody, with potential antineoplastic activity. Upon administration, anti-CD33 monoclonal antibody BI 836858 induces an antibody-dependent cellular cytotoxicity (ADCC) against CD33-expressing tumor cells, leading to cell death. CD33, a cell surface antigen expressed on normal non-pluripotent hematopoietic stem cells, is overexpressed on myeloid leukemia cells.;

UNII : JA7I0QFJ17;

CAS number : 2206770-25-2;

Molecule name : BI 836858;

NCI Metathesaurus CUI : CL446627;

Détails

Origin ID

C116737;

UMLS CUI

C3896902;

Currated CISMeF NLP mapping
- BI 836858 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BI 836858 [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Myeloid Cell Surface Antigen CD33 [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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