Anti-CD33 Monoclonal Antibody BI 836858NCIt concept
Preferred Label : Anti-CD33 Monoclonal Antibody BI 836858;
NCIt related terms : BI-836858;
NCIt definition : An engineered, fully human, immunoglobulin (Ig) G1 anti-CD33 monoclonal antibody,
with potential antineoplastic activity. Upon administration, anti-CD33 monoclonal
antibody BI 836858 induces an antibody-dependent cellular cytotoxicity (ADCC) against
CD33-expressing tumor cells, leading to cell death. CD33, a cell surface antigen expressed
on normal non-pluripotent hematopoietic stem cells, is overexpressed on myeloid leukemia
cells.;
UNII : JA7I0QFJ17;
CAS number : 2206770-25-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2206770-25-2
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