Rocakinogene Sifuplasmid

Preferred Label : Rocakinogene Sifuplasmid;

NCIt synonyms : DNA Plasmid Encoding Interleukin-12 INO-9012;

NCIt definition : A plasmid DNA vaccine encoding the human pro-inflammatory cytokine interleukin-12 (IL-12) with potential immunoactivating activity. Upon intramuscular delivery by electroporation of rocakinogene sifuplasmid, IL-12 is translated in cells and activates the immune system by promoting the activation of natural killer cells (NK cells), inducing secretion of interferon-gamma and promoting cytotoxic T-cell responses against tumor cells. This may result in both immune-mediated tumor cell death and the inhibition of tumor cell proliferation.;

UNII : 91JHE0ANN8;

CAS number : 2253753-17-0;

Molecule name : INO-9012;

NCI Metathesaurus CUI : CL473906;

Détails

Origin ID

C116709;

UMLS CUI

C5418156;

Currated CISMeF NLP mapping
- rocakinogene sifuplasmid [MeSH Supplementary Concept]
- rocakinogene sifuplasmid [MeSH concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Nucleic Acid, Nucleoside, or Nucleotide [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- rocakinogene sifuplasmid [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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