" /> Rocakinogene Sifuplasmid - CISMeF





Preferred Label : Rocakinogene Sifuplasmid;

NCIt synonyms : DNA Plasmid Encoding Interleukin-12 INO-9012;

NCIt definition : A plasmid DNA vaccine encoding the human pro-inflammatory cytokine interleukin-12 (IL-12) with potential immunoactivating activity. Upon intramuscular delivery by electroporation of rocakinogene sifuplasmid, IL-12 is translated in cells and activates the immune system by promoting the activation of natural killer cells (NK cells), inducing secretion of interferon-gamma and promoting cytotoxic T-cell responses against tumor cells. This may result in both immune-mediated tumor cell death and the inhibition of tumor cell proliferation.;

UNII : 91JHE0ANN8;

CAS number : 2253753-17-0;

Molecule name : INO-9012;

NCI Metathesaurus CUI : CL473906;

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29/07/2025


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