NCIt definition : A non-metabolizable glucose analog in which the hydroxyl group at position 2 of glucose
is replaced by hydrogen, with potential glycolysis inhibiting and antineoplastic activities.
Although the exact mechanism of action has yet to be fully elucidated, upon administration
of 2-deoxy-D-glucose (2-DG), this agent competes with glucose for uptake by proliferating
cells, such as tumor cells. 2-DG inhibits the first step of glycolysis and therefore
prevents cellular energy production, which may result in decreased tumor cell proliferation.;
UNII : 9G2MP84A8W;
CAS number : 154-17-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 154-17-6
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