PDGFR-BB - CISMeF

Preferred Label : PDGFR-BB;

NCIt synonyms : Platelet-Derived Growth Factor Receptor Beta Homodimeric Complex;

NCIt definition : A homodimeric protein complex comprised of 2 platelet-derived growth factor receptor beta proteins. Formation of this complex is dependent on the binding of a disulfide-linked homodimer of platelet-derived growth factor beta. The formation of the receptor dimer activates its intrinsic tyrosine-protein kinase activity and initiates signal transduction pathways.;

Details

Origin ID

C116395;

UMLS CUI

C3898049;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_plays_role_in_biological_process
- Receptor Signaling [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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