Preferred Label : 5-FITC-labeled Colon-Heptapeptide;
NCIt synonyms : KCCFPAQ-GGGSK-(5-FITC)-NH2;
NCIt definition : A radioconjugate consisting of a 7 amino acid peptide sequence, KCCFPAQ, that specifically
targets human colon cancer and labeled, via the linker, GGGSK, with the fluorescent
dye, fluorescein isothiocyanate (5-FITC), with potential imaging activity. Following
spray application to the colon wall during colonoscopy in areas that look abnormal,
the colon heptapeptide moiety of 5-FITC-labeled colon-heptapeptide specifically targets
and binds to a cell surface target overexpressed on pre-cancerous or cancerous colon
cells. Upon internalization, the FITC moiety allows for fluorescent imaging and the
area of interest for biopsies can then be visualized.;
NCI Metathesaurus CUI : CL473672;
Origin ID : C116354;
UMLS CUI : C3900197;
Semantic type(s)
- concept_is_in_subset
