Preferred Label : Synthetic Glioblastoma Tumor-associated Peptides Vaccine Therapy APVAC1;
NCIt definition : A personalized peptide-based cancer vaccine comprised of five to ten peptides associated
with glioblastoma (GB), with potential immunomodulating and antineoplastic activities.
Vaccination with synthetic GB tumor-associated peptides vaccine therapy APVAC1 stimulates
the host immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor
cells expressing the tumor associated peptides, and results in decreased GB growth.
The peptides are derived from a glioma actively personalized vaccine consortium (GAPVAC)
warehouse and are specifically selected based on the patient's expression of tumor-associated
antigens.;
Molecule name : APVAC1;
NCI Metathesaurus CUI : CL473665;
Origin ID : C116331;
UMLS CUI : C3896915;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
- concept_is_in_subset
