N-Methylformamide

Preferred Label : N-Methylformamide;

NCIt synonyms : formylmethylamine; Formamide, N-methyl; NMF;

NCIt related terms : EK 7011; Monomethylformamide; X 188;

NCIt definition : A water-soluble organic solvent. As an adjuvant antineoplastic agent, N-methylformamide depletes cellular glutathione, a key molecule involved in the antioxidation of reactive oxygen species (ROS) and other free radicals, thereby enhancing ionizing radiation-induced DNA cross-linking in and terminal differentiation of tumor cells. (NCI04);

UNII : XPE4G7Y986;

InChIKey : ATHHXGZTWNVVOU-UHFFFAOYSA-N;

CAS number : 123-39-7;

Molecule name : EK 7011; X 188;

Chemical formula : C2H5NO;

NSC code : 3051;

ChEBI ID : CHEBI:7438;

Codes from synonyms : NSC0003051; 01885;

Details

Origin ID

C1163;

UMLS CUI

C0066373;

Automatic exact mappings (from CISMeF team)
- Methyl formamide [LOINC component]
- methylformamide [Substance BNPC]
- methylformamide [MeSH Supplementary Concept]
- methylformamide [MeSH concept]
Currated CISMeF NLP mapping
- N-methylformamide (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Methyl formamide [LOINC component]
- N-methylformamide (substance) [SNOMED CT concept]
- methylformamide [Substance BNPC]
- methylformamide [MeSH concept]
- methylformamide [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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