NCIt related terms : PRAB; PRA Score; Panel Reactive Antibody;
NCIt definition : An assessment of the reactivity between host immune cells and donor human leukocyte
antigen. This test is most commonly carried out in subjects awaiting transplant. The
recipient's blood or serum is mixed with either a panel of lymphocytes from random
blood donations or a potential donor's purified human leukocyte antigens (HLA). Host
reactivity is scored as a percent.;
Alternative definition : CDISC: A measurement of the panel reactive antibody that is achieved by mixing and
assessing the reactivity between the recipient's immune cells and the donor's human
leukocyte antigen, in which anti-HLA class I and class II antibody specificities are
measured separately in a biological specimen.;