Preferred Label : ACC/AHA Ischemic ECG Changes;
NCIt related terms : CV ENDPOINTS ISCHEMIC ECG CHANGES;
NCIt definition : An electrocardiographic finding, in the absence of left ventricular hypertrophy (LVH)
and left bundle branch block pattern on ECG, of either a) new (or presumed new) ST
elevation at the J point in two contiguous leads with the following cut-points: greater
than or equal to 0.1 mV in all leads other than leads V2-V3 where the following cut
points apply: greater than or equal to 0.2 mV in men age greater than or equal to
40 years, greater than or equal to 0.25 mV in men age greater than 40 years, or greater
than or equal to 0.15 mV in women; or b) new (or presumed new) horizontal or down-sloping
ST depression greater than or equal to 0.05 mV in two contiguous leads, and/or T wave
inversion greater than or equal to 0.1 mV in two contiguous leads with a prominent
R wave, or R/S ratio greater than 1. (Thygesen K, Alpert JS, Jaffe AS, et al.: the
Writing Group on behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the Universal
Definition of Myocardial Infarction. J Am Coll Cardiol 60(16):1-18, 2012);
Alternative definition : CDISC: An electrocardiographic finding, in the absence of left ventricular hypertrophy
(LVH) and left bundle branch block pattern on ECG, of either a) new (or presumed new)
ST elevation at the J point in two contiguous leads with the following cut-points:
greater than or equal to 0.1 mV in all leads other than leads V2-V3 where the following
cut points apply: greater than or equal to 0.2 mV in men greater than or equal to
40 years; greater than or equal to 0.25 mV in men less than 40 years, or greater than
or equal to 0.15 mV in women; or b) new (or presumed new) horizontal or down-sloping
ST depression greater than or equal to 0.05 mV in two contiguous leads and/or T inversion
greater than or equal to 0.1 mV in two contiguous leads with prominent R wave or R/S
ratio greater than 1. (Thygesen K, Alpert JS, Jaffe AS, Simoons ML, et al.; Joint
ESC/ACCF/AHA/WHF Task Force for Universal Definition of Myocardial Infarction. Third
universal definition of myocardial infarction. J Am Coll Cardiol. 2012 Oct 16;60(16):1581-98).;
Origin ID : C116138;
UMLS CUI : C3900169;
Semantic type(s)
concept_is_in_subset