Preferred Label : Melanoma-Associated Antigen Family A;
NCIt synonyms : MAGEA; MAGE A Family; Class 1 Melanoma-Associated Antigen Family A; MAGE-A; Melanoma Antigen, Family A;
NCIt definition : A family of 12 proteins whose members were first detected in male germ cells, placenta
and various tumors but originally not found in normal tissues. Their genes are located
in the vicinity of Xq28. All of the members of the family share a stretch of about
200 amino acids, called the MAGE conserved domain, which is usually located near the
C-terminal end of the protein and may allow these proteins to interact with cellular
receptors.;
Origin ID : C116017;
UMLS CUI : C3898431;
Semantic type(s)
- concept_is_in_subset
