NCIt definition : A fusion gene that results from a chromosomal translocation t(17;21)(q21;q22) which
fuses the 5' untranslated region of the TMPRSS2 gene upstream of exon 3 of the ETV4
gene. This rearrangement is associated with prostate carcinoma and androgen-dependent
expression of this fusion gene results in overexpression of ETS translocation variant
4 protein activity.;