TLR9 Agonist DUK-CPG-001

Preferred Label : TLR9 Agonist DUK-CPG-001;

NCIt definition : A synthetic CpG-rich oligonucleotide with potential immunopotentiating activity. TLR9 agonist DUK-CPG-001 binds to and activates intracellular toll-like receptor 9 (TLR9) in monocytes/macrophages, plasmacytoid dendritic cells (DCs), natural killer (NK) cells and B-cells. This initiates immune signaling pathways, activates DCs, NK cells and B-cells, and induces both the production of T-helper 1 cells (Th1) and a Th1-mediated immune response. TLR9 is a member of the TLR family, which plays a key role in both pathogen recognition and the activation of innate immunity.;

Molecule name : DUK-CPG-001;

NCI Metathesaurus CUI : CL473296;

Details

Origin ID

C115959;

UMLS CUI

C3896868;

Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Toll-Like Receptor 9 [NCIt concept]

Keyword's position in hierarchy(ies) :

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