Preferred Label : GM2-KLH Vaccine/QS21;
NCIt synonyms : GM2-KLH/QS21; GM2-KLH/QS-21; GMK; GM2-KLH-Vaccine QS21;
NCIt definition : A cancer vaccine based on the immunogenic ganglioside GM2, The GM2-KLH Vaccine/QS21
vaccine consists of GM2 conjugated with KLH keyhole limpet hemocyanin (KLH), a potent
immunostimulant, and is admixed with the adjuvant QS21, a saponin fraction extracted
from the bark of the South American tree Quillaja saponaria Molina. GM2 is a cell
surface carbohydrate antigen expressed by most melanoma cells and various other tumor
cell types. (NCI04);
Origin ID : C11571;
UMLS CUI : C0338324;
Semantic type(s)
concept_is_in_subset