Belapectin - CISMeF

Preferred Label : Belapectin;

NCIt synonyms : Galactoarabino-rhamnogalacturonate;

NCIt definition : A carbohydrate-based galectin inhibitor, with potential antineoplastic activity. Belapectin binds to the carbohydrate-binding domain of galectins, especially galectin-3, and may result in an induction of apoptosis mediated through activation of both mitochondria and caspases. This may reduce tumor growth in galectin-overexpressing tumor cells. Galectins, often overexpressed on tumor cells, play a key role in cancer cell proliferation, apoptosis, tumor angiogenesis and evasion of immune responses.;

UNII : K7ODU55HT6;

CAS number : 1980787-47-0;

Molecule name : GR-MD-02;

NCI Metathesaurus CUI : CL472642;

Details

Origin ID

C115111;

UMLS CUI

C5139836;

Currated CISMeF NLP mapping
- belapectin [MeSH Supplementary Concept]
- belapectin [MeSH concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- belapectin [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Galectin-3 [NCIt concept]

Keyword's position in hierarchy(ies) :

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