HTR2C wt Allele

Preferred Label : HTR2C wt Allele;

NCIt synonyms : RP11-810O3.1; 5-HT2C; HTR1C; 5-HTR2C; 5-Hydroxytryptamine (Serotonin) Receptor 2C, G Protein-Coupled wt Allele; 5HTR2C; 5-Hydroxytryptamine (Serotonin) Receptor 2C Gene; Serotonin 5-HT-1C Receptor, Formerly Gene;

NCIt definition : Human HTR2C wild-type allele is located in the vicinity of Xq23 and is approximately 326 kb in length. This allele, which encodes 5-hydroxytryptamine receptor 2C protein, plays a role in serotonin binding and signaling. This gene undergoes RNA deamination at sites designated A, B, C-prime, E, C, and D; RNA editing at sites C, D and C-prime may be associated with depression.;

GenBank Accession Number : NM_000868;

Details

Origin ID

C115017;

UMLS CUI

C3889121;

Automatic exact mappings (from CISMeF team)
- 5-hydroxytryptamine receptor 2c [OMIM gene]
- receptor, serotonin, 5-ht2c [MeSH Descriptor]
OMIM relation
- 5-hydroxytryptamine receptor 2c [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Calcium Signaling [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Neurologic Process [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Nucleotide Biosynthesis Process [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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