FERMT2 wt Allele

Preferred Label : FERMT2 wt Allele;

NCIt synonyms : mig-2; Fermitin Family Member 2 wt Allele; PLEKHC1; UNC112B; Mitogen-Inducible Gene 2; Pleckstrin Homology Domain Containing, Family C (With FERM Domain) Member 1 Gene; Fermitin Family Homolog 2 (Drosophila) Gene; UNC112; Fermitin Family (Drosophila) Homolog 2 Gene; KIND2; Unc112, C. Elegans, Homolog of Gene; MIG2;

NCIt definition : Human FERMT2 wild-type allele is located in the vicinity of 14q22.1 and is approximately 95 kb in length. This allele, which encodes fermitin family homolog 2 protein, plays a role in both the assembly of focal adhesions and integrin signaling.;

NCIt note : There is a report of a chromosomal aberration involving the ERO1L gene and the FERMT2 gene, which is associated with breast cancer. (COSMIC);

GenBank Accession Number : Z24725;

Details

Origin ID

C114608;

UMLS CUI

C3889283;

Automatic exact mappings (from CISMeF team)
- 2-(1-hydroxyethyl)-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran glucuronide [MeSH Supplementary Concept]
- FERM domain containing kindlin 3 [ORDO Gene]
- Ferm domain-containing kindlin 2 [OMIM gene]
OMIM relation
- Ferm domain-containing kindlin 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Cell-Matrix Adhesion Process [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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