PRKAR2A wt Allele

Preferred Label : PRKAR2A wt Allele;

NCIt synonyms : PRKAR2; PKR2; Protein Kinase, cAMP-Dependent, Regulatory, Type II, Alpha wt Allele;

NCIt definition : Human PRKAR2A wild-type allele is located within 3p21.3-p21.2 and is approximately 103 kb in length. This allele, which encodes cAMP-dependent protein kinase type II-alpha regulatory subunit protein, plays a role in the modulation of cyclic AMP-dependent signaling.;

NCIt note : There is a report of a chromosomal aberration involving the SLC26A6 gene and the PRKAR2A gene, which is associated with breast cancer. (COSMIC);

GenBank Accession Number : NM_004157;

Details

Origin ID

C114543;

UMLS CUI

C3889384;

Automatic exact mappings (from CISMeF team)
- Prokineticin receptor 2 [OMIM gene]
- Protein kinase, camp-dependent, regulatory, type II, beta [OMIM gene]
- prokineticin receptor 2 [ORDO Gene]
OMIM relation
- Protein kinase, camp-dependent, regulatory, type II, alpha [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3p21.3-p21.2 [NCIt concept]
gene_is_element_in_pathway
- Apoptosis Pathway [NCIt concept]
- Attenuation of GPCR Signaling Pathway [NCIt concept]
- BAD Regulation Pathway [NCIt concept]
- CARM1 Transcription Regulation Pathway [NCIt concept]
- CFTR Pathway [NCIt concept]
- CK1/CDK5 Regulation Pathway [NCIt concept]
- CREB Activation Signaling Pathway [NCIt concept]
- CSK Protein Kinase Activation Pathway [NCIt concept]
- Calpain-2 Cell Motility Pathway [NCIt concept]
- Centrosome Pathway [NCIt concept]
- ChREBP Pathway [NCIt concept]
- G-Protein Signaling Pathway [NCIt concept]
- IGF1R Antiapoptosis Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Nitric Oxide Pathway [NCIt concept]
- Nitric Oxide Signaling Pathway [NCIt concept]
- Oocyte Maturation Pathway [NCIt concept]
- Pain Repression Pathway [NCIt concept]
- Phospholipase C-Epsilon Signaling Pathway [NCIt concept]
- Protein Kinase A Activation Pathway [NCIt concept]
- Stathmin Pathway [NCIt concept]
- Stress Fiber Formation Pathway [NCIt concept]
- T-Cell Antiapoptosis Pathway [NCIt concept]
- Th2 Cytokine Gene Induction Pathway [NCIt concept]
gene_plays_role_in_process
- Protein Kinase Protein Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Transmembrane Transport [NCIt concept]

Keyword's position in hierarchy(ies) :

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