Macrophage Activation Syndrome

Preferred Label : Macrophage Activation Syndrome;

NCIt related terms : MAS; Reactive Hemophagocytic Lymphohistiocytosis;

NCIt definition : A complication of rheumatic disease that is caused by excessive activation and uncontrolled proliferation of T lymphocytes and well-differentiated macrophages. It is characterized by fever, pancytopenia, liver insufficiency, coagulopathy and neurologic symptoms.;

Alternative definition : NICHD: A potentially fatal complication of rheumatic disease characterized by fever, pancytopenia, hemophagocytosis, hyperferritinemia, liver insufficiency, coagulopathy and neurologic symptoms.;

Details

Origin ID

C114471;

UMLS CUI

C1096155;

Automatic exact mappings (from CISMeF team)
- Mas1 oncogene [OMIM gene]
- Mccune-albright syndrome [OMIM Phenotype]
- Neonatal aspiration of meconium [ICD-11 Subcategory]
- microtubule organizing center attachment site [GO term]
Currated CISMeF NLP mapping
- Hemophagocytic lymphohistiocytosis [ICD-10 Sub-category]
- Hemophagocytic lymphohistiocytosis (disorder) [SNOMED CT concept]
- Hemophagocytic syndrome [PASCAL descriptor]
- Macrophage activation syndrome [MedDRA LLT]
- Macrophage activation syndrome [ORDO Disease]
- Macrophage activation syndrome (disorder) [SNOMED CT concept]
- haemophagocytic lymphohistiocytosis [COVID-19 Thesaurus concept]
- hemophagocytic lymphohistiocytosis [DO Concept]
- macrophage activation syndrome [MeSH Descriptor]
- macrophage activation syndrome [MeSH concept]
- macrophage activation syndrome [Artificial nutrition thesaurus concept]
- macrophage activation syndrome [Disease (Nov.)]
False automatic mappings
- Ashworth assessment scale (assessment scale) [SNOMED CT concept]
See also inter- (CISMeF)
- Haemophagocytic syndrome [MedDRA LLT]
- Hemophagocytic syndrome (disorder) [Inactive SNOMED CT concept]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Macrophage activation syndrome [ORDO Disease]
- Macrophage activation syndrome [MedDRA LLT]
- Macrophage activation syndrome (disorder) [SNOMED CT concept]
- macrophage activation syndrome [MeSH Descriptor]
- macrophage activation syndrome [MeSH concept]
- macrophage activation syndrome [Disease (Nov.)]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Adverse Events Terminology [NCIt concept]
- Pediatric Adverse Events Terminology Mapped to MedDRA [NCIt concept]
- Pediatric Rheumatology Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients